Applications of Synthetic Biology in Microbial Biotechnology

نویسندگان

  • Hal Alper
  • Patrick Cirino
  • Elke Nevoigt
  • Ganesh Sriram
چکیده

1Department of Chemical Engineering, The University of Texas at Austin, 1 University Station, C0400, Austin, TX 78712, USA 2Department of Chemical Engineering, The Pennsylvania State University, 226A Fenske Laboratory, University Park, PA 16802-4400, USA 3Department of Chemical and Biomolecular Engineering, University of Maryland, 1208D, Chemical and Nuclear Engineering Building 090, College Park, MD 20742, USA 4Molecular Biotechnology, Jacobs University gGmbH, School of Engineering and Science, Research II Room 113, Campus Ring 1, 28759 Bremen, Germany

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Engineering microbial consortia: a new frontier in synthetic biology.

Microbial consortia are ubiquitous in nature and are implicated in processes of great importance to humans, from environmental remediation and wastewater treatment to assistance in food digestion. Synthetic biologists are honing their ability to program the behavior of individual microbial populations, forcing the microbes to focus on specific applications, such as the production of drugs and f...

متن کامل

Ethical Debates on Synthetic Biology

Background: As an emerging interdisciplinary area of science with a multitude of potential facilities and applications, synthetic biology integrates different disciplines with one another ranging from basic science to engineering. This interdisciplinary branch therefore encompasses sciences that require specific development and ethical approaches. Materials and Methods: Science management princ...

متن کامل

Principles for designing synthetic microbial communities.

Advances in synthetic biology to build microbes with defined and controllable properties are enabling new approaches to design and program multispecies communities. This emerging field of synthetic ecology will be important for many areas of biotechnology, bioenergy and bioremediation. This endeavor draws upon knowledge from synthetic biology, systems biology, microbial ecology and evolution. F...

متن کامل

Design, analysis and application of synthetic microbial consortia

The rapid development of synthetic biology has conferred almost perfect modification on single cells, and provided methodological support for synthesizing microbial consortia, which have a much wider application potential than synthetic single cells. Co-cultivating multiple cell populations with rational strategies based on interacting relationships within natural microbial consortia provides t...

متن کامل

Microbially derived biosensors for diagnosis, monitoring and epidemiology

Living cells have evolved to detect and process various signals and can self-replicate, presenting an attractive platform for engineering scalable and affordable biosensing devices. Microbes are perfect candidates: they are inexpensive and easy to manipulate and store. Recent advances in synthetic biology promise to streamline the engineering of microbial biosensors with unprecedented capabilit...

متن کامل

Advancing bacteriophage-based microbial diagnostics with synthetic biology.

Figure 1. Engineered bacteriophages can be assembled into sensitive, specific, and rapid microbial diagnostics. (A) Bacteriophages can be designed to express reporter payloads during specific microbial infection, leading to the production of detectable outputs. (B) Designing synthetic bacteriophages as microbial Synthetic biology is an emerging engineering field focused on designing artificial ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 2010  شماره 

صفحات  -

تاریخ انتشار 2010